Pillar article

What is photobiomodulation?

LED masks, light beds, overlay mattresses: red and infrared light is everywhere in aesthetics. What do we actually know about its effects on the skin?

In short

Photobiomodulation is the use of low-intensity red or near-infrared light to modify cell activity. Light is absorbed mainly by mitochondrial molecules. Effects are reported in dermatology on skin quality and healing, with evidence that varies by indication.

The described mechanism

According to reference work, red and near-infrared photons are absorbed by mitochondrial chromophores, notably cytochrome c oxidase, leading to increased cellular energy (ATP), nitric oxide release, increased local blood flow and activation of signalling pathways involved in tissue repair [1].

Red or infrared?

Red light (around 630–660 nm) acts mainly in superficial skin layers; near-infrared (above 800 nm) penetrates deeper. Many devices combine both; AdipoXtrem uses 635 nm (red) and 980 nm (infrared).

What cannot be claimed

The evidence does not support presenting LED alone as a way to “eliminate” fat or “toxins”. In a combined device, it is a complementary part of the session.

Sources

  1. Avci P, Gupta A, Sadasivam M, et al. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med Surg. 2013;32(1):41-52. PMC4126803

Reference identified via PubMed. For information only; not medical advice.

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